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KMID : 0361020180610120692
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Korean Journal of Otolaryngology - Head and Neck Surgery
2018 Volume.61 No. 12 p.692 ~ p.696
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Analysis of Relationship between Reflux Symptom Index and Psychiatric Problems
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Park In-Jun
Kang Jun-Myung
Seo Jae-Hyun
Hwang Sang-Hyun
Youn Ho-Young
Jin Ho-Jun
Kang Ha-Ram
Joo Young-Hoon
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Abstract
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Background and Objectives: This study investigated the relationship between reflux symptom index (RSI) and psychiatric problems such as depression, somatization, and anxiety.
Subjects and Method: We prospectively analyzed 231 patients with symptoms with laryngopharyngeal reflux (LPR) using the RSI and the reflux finding score.
Results: Seventy nine patients (34.2%) were diagnosed with LPR. A significant correlation was detected between the RSI and depression (18.4±8.3 vs. 12.3±7.0, p<0.001), anxiety (19.5± 8.5 vs. 13.0±7.3, p<0.001), and somatization (19.2±9.1 vs. 13.6±7.5, p<0.001). A multivariate analysis confirmed a significant association between heartburn and depression [odds ratio (OR): 1.241, 95% confidence interval (CI): 1.003-1.537, p=0.047], choking and anxiety (OR: 1.747, 95% CI: 1.297-2.352, p<0.001), and choking and somatization (OR: 1.707, 95% CI: 1.248-2.336, p=0.001).
Conclusion: Our preliminary results suggest that patients with high RSI may need to be carefully evaluated for psychiatric problems.
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KEYWORD
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Anxiety, Depression, Laryngopharyngeal reflux, Somatoform disorders
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